It is possible to trigger content in a zone based on content in other zones.
Setup your playlist.
Here is an example playlist with two zones.
In this example we will make a picture of a gumtree display whenever the koala is displaying.
You can see in the second zone we just have a few basic images scrolling through
We now need to add the gumtree asset, we'll add it to the 'triggered' content tab, then click the cog icon when hovering over the asset to bring up the properties.
We then add in the filename of the koala asset where indicated in the image screenshot.
Save, deploy as normal